There chronic low back pain is a condition that affects many people around the world. This is why researchers were interested in the effects of cannabidiol (CBD) to relieve this persistent pain. Known for its multiple medicinal properties, there appears to be an interaction between CBD and chronic low back pain. In this article we will decipher the studies carried out on the subject.
- Overview of Chronic Low Back Pain
- Why use CBD?
- The CBD and pain interaction
- CBD as an alternative to morphine
- Troubleshooting Drug Interaction Issues
1. Overview of chronic low back pain
Chronic low back pain is defined by persistent pain in the lumbar spine (lower back), lasting more than three months. It can be caused by many reasons such as:
- Muscle tension due to poor posture or a wrong movement,
- A herniated disc,
- Tendon or ligament disorders,
- An anatomical problem affecting in particular the intervertebral discs or the nerves at the level of the vertebrae.
The main treatment for this pain is based on taking anti-inflammatories, painkillers and sometimes even opioids. However, the side effects of these treatments can be dangerous for some patients and lead to opioid addiction. This is why an alternative is being sought.
2. Why use CBD?
Coming from Cannabis sativa L, the CBD (cannabidiol) is one of the hundreds of cannabinoids present in this plant. Unlike THC, it has no psychoactive effect and is known for its many medicinal properties:
- Anti-inflammatory,
- Antioxidant,
- Immunoregulator,
- Anxiolytic.
CBD is used in different ways: orally, topically, inhaled or even vaporized. Several scientific studies have demonstrated that CBD could help reduce the intensity of various chronic pain by acting directly on the patient’s nervous system.
3. The CBD and pain interaction
Action on the endocannabinoid system
The main mechanism of action of CBD against pain is its interaction with the endocannabinoid system present in our body. This regulates many functions, including the perception of pain.
CBD acts in particular on the CB1 and CB2 receptors of the endocannabinoid system, reducing inflammation and the sensation of pain felt by the patient. Several studies have demonstrated that cannabidiol could reduce intensity various chronic pains such as fibromyalgia or postherpetic neuralgia.
A multi-target approach
In addition to its action on the endocannabinoid system, CBD presents a variety of beneficial effects for the treatment of chronic low back pain:
- Improvement in the quality of sleep, often disturbed in patients suffering from low back pain,
- Reduced anxiety, often associated with chronic pain,
- Supports the immune system.
4. CBD as an alternative to morphine
Opioids such as morphine are often prescribed to treat the severe pain caused by chronic low back pain. However, these medications carry a high risk of dependence andside effects serious.
CBD then appears to be an interesting alternative thanks to its analgesic properties without major side effects and does not present any risk of addiction. Several studies show that CBD could enhance the effectiveness of opioids, thus making it possible to reduce the doses administered.
Mutual potentiation
The action of CBD on CB1 and CB2 receptors potentiates that of opioids by increasing their effectiveness. This allows to reduce the dose of opioids needed to relieve pain, thus limiting the risks of side effects and dependence. Thus, some patients could benefit from a combination of CBD and low-dose opioids for greater relief of their chronic low back pain pain.
5. Resolving drug interaction issues
As with any drug treatment, it is essential to evaluate the possible interactions between CBD and other medications taken by the patient. CBD is known to interact with certain medications metabolized by the liver.
Nevertheless, good communication between the doctor and his patient is crucial for safe treatment. If you suffer from chronic low back pain and want to try CBD, talk to your doctor who will be able to adjust your treatments and ensure that there are nodrug interactions.
In summary, CBD appears to be a promising alternative to relieve chronic low back pain by modulating the endocannabinoid system while avoiding the side effects and risks of addiction associated with opioids. However, it is essential to supervise its use with the help of a healthcare professional, in order to avoid any unwanted drug interactions.
