Le cannabidiol, or CBD, is a recognized neuroprotectant. The Alzheimer's disease causing the death of neurons, the interest of CBD to relieve its symptoms seems obvious. However, the scientific literature on the subject is still thin and it remains difficult to know its exact effects. So can CBD relieve Alzheimer's symptoms and, in doing so, limit the loss of autonomy sick people ? This is our topic of the day.
CBD: a neuroprotector to support Alzheimer's patients?
Among therapeutic effects of CBD, we count its action on neurological diseases. This concerns both neuropsychiatric illnesses (autism spectrum disorders, schizophrenia, depression) and neurodegenerative diseases so are part of Alzheimer's, multiple sclerosis, Huntington's disease andepilepsy.
Cannabidiol would thus have neuroprotective properties and the ability toimprove cognitive abilities of its consumers, particularly in the context of familial forms of Alzheimer's disease. Hemp consumption could also, in some cases, stimulate neurogenesis (growth of new cells in the brain).
In addition to this, CBD does not present no side effects major known. This is all the more important since the current treatments for Alzheimer's disease do not prevent the onset of the disease or cure it. They are therefore only more or less effective means of slow it down or lessen its symptoms, at the risk of more or less serious side effects.
The properties of CBD, certainly potentially beneficial in the context of Alzheimer's disease, do not, at this stage, constitute any hope of treatment either. They could, however, improve the daily life of patients. Let's first look at what the pathology is and how it manifests itself, before better understanding the hopes raised by taking cannabidiol and other cannabinoids.
Alzheimer's disease in brief
Alzheimer's disease is the most common form of dementia, in front of Parkinson's disease (moreover sometimes treated with CBD). In France, it affects approximately 1,2 million people. This figure, already significant, is only increasing since the proportion of sick people increases with age. As the population is aging, Alzheimer's should affect 2,2 million people in France by 2050. Indeed, before the age of 70, the disease affects less than one in 100 people. Beyond the age of 90, the proportion increases to one in three people.
Beyond the figures, it is the symptoms and the lack of treatment options that constitute the greatest difficulties for the people concerned, sick and those around them.
- Memory loss.
- Difficulty performing everyday tasks (using numbers, following a recipe, concentrating on any activity).
- Difficulty finding one's bearings in time and space (confusion of dates, seasons, forgetting where one is).
- Communication problems, both oral and written.
- Difficulty or inability to remember where you just put an object.
- Difficulty judging a situation reasonably.
- Mood and personality disorders (confusion, depression, anxiety, etc.).
Causes of Alzheimer's disease
The causes of Alzheimer's disease are still poorly understood. However, it has been established that neurons suffer from two types of damage:
- The amyloid plaques, or senile plaques, formed due to an excessive accumulation of β-amyloid protein, are deposited in the cerebral cortex and prevent a normal connection between neurons.
- The neurofibrillary tangles, formed due to an excessive accumulation of filaments inside neurons, lead to the death of neurons at the level of the hippocampus (associated with the proper functioning of memory) and the associative cortex, linking the different functions together.
As a direct consequence, the brain atrophies, causing the symptoms mentioned above. The causes of the onset of the disease are relatively unknown. Of the genetic factors have been highlighted. However, they only concern 5% of cases. L'age, cardiovascular problems, sleeping troubles and certain environmental factors (alcohol, drugs, pollution, certain drug treatments) finally seem to constitute risk factors.
CBD to relieve Alzheimer's symptoms?
Research on the action of CBD on Alzheimer's symptoms is still at an early stage. Nevertheless, two axes seem to arouse the interest of researchers: the effects of CBD about the disease herself as well as on the quality of life of patients.
Improve cognitive functions
According to an article in the Journal of Alzheimer's disease, taking CBD in the context of Alzheimer's could improve TREM2 and IL-3 levels, two proteins that play an essential role in the elimination of waste and beta-amyloid plaques that accumulate in the framework of the disease and encourage the inflammation and then the death of neurons.
Finding a better quality of life
Wider, buy CBD can help provide a better quality of life for Alzheimer's patients.
- Reduce the anxiety disorders and depressed: CBD encourages the production of serotonin, a substance produced by certain neurons and active in the management of emotions.
- Find a better quality of sleep: taking CBD helps to rebalance our internal clock, promoting both falling asleep and the quality of sleep.
Which CBD product for Alzheimer's?
There are all kinds of CBD products, more or less concentrated and whose mode of taking is more or less healthy. To cope with the symptoms of Alzheimer's disease, theCBD oil seems the most appropriate. She is indeed easy to use (a few drops under the tongue are enough), healthy (no combustion or smoke development) and offers visible effects thanks to the numerous concentrations available.
Associated with hemp oil, the CBD also has the merit of adding the properties of hemp. It naturally contains Vitamin E (helpful in preventing cognitive decline), Fatty acids (which can postpone the onset of certain disorders) and omegas, useful against stress and anxiety.